Retatrutide
Retatrutide (LY3437943) — GLP-1 / GIP / glucagon triple agonist for metabolic research.
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Compound Information
A synthetic triple-agonist research peptide with activity at GLP-1, GIP, and glucagon receptors. Investigated in metabolic-research models exploring combined incretin and glucagon signaling.
- Category
- Synthetic Peptide
- Molecular Formula
- C221H343N51O64
- Molecular Weight
- ≈ 4731 Da
- Target
- GLP-1R, GIPR, GCGR (triple-agonist)
- Storage
- −20°C lyophilized; 2–8°C reconstituted
- Solubility
- Bacteriostatic water (recommended)
Sources & References
Reference literature for the compound's biochemistry. Citations are general mechanism context — not therapeutic claims.
Triple-agonist receptor pharmacology
Mechanism literature on simultaneous engagement of GLP-1, GIP, and glucagon receptors.
Incretin-axis signaling
Reviews of GLP-1R and GIPR downstream pathways in research models.
For research use only. The information above is provided for laboratory and academic reference. Not intended to diagnose, treat, cure, or prevent any condition. See our Research Use Only policy.
Certificate of Analysis
Third-party HPLC purity testing for this compound. Download the full-resolution certificates below.
Independently HPLC-tested for identity, purity, and concentration.
